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Article

Interplay between the androgen receptor signaling axis and microRNAs in prostate cancer

26 Feb 2019

Abstract excerpt

The androgen receptor (AR) is a ligand-activated transcription factor that drives prostate cancer. Since therapies that target the AR are the mainstay treatment for men with metastatic disease, it is essential to understand the molecular mechanisms underlying oncogenic AR signaling in the prostate. miRNAs are small, non-coding regulators of gene expression that play a key role in prostate cancer and are...

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PMID: 30817318
DOI: 10.1530/erc-18-0571

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