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Association of PTPN1 polymorphisms with breast cancer risk: A case‐control study in Chinese females

25 Feb 2019

Abstract excerpt

Abstract Background Breast cancer (BC) risk, development, and prognosis were closely related to obesity, diabetes mellitus, and metabolic syndrome. Protein tyrosine phosphatase, non‐receptor type 1 (PTPN1) located on chromosome 20q13, could negatively regulate insulin and leptin signaling. In this study, we determined the association of PTPN1 polymorphisms with BC risk. Methods We analyzed the distribution of 11...

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PMID: 30805963
DOI: 10.1002/jcb.28490

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