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Article

Genomic Epidemiology of Penicillin-Nonsusceptible Pneumococci with Nonvaccine Serotypes Causing Invasive Disease in the United States.

Journal of clinical microbiology - 1 Apr 2017

Andam Cheryl P, Mitchell Patrick K, Callendrello Alanna, Chang Qiuzhi, Corander Jukka, Chaguza Chrispin, McGee Lesley, Beall Bernard W, Hanage William P

Abstract excerpt

Conjugate vaccination against seven pneumococcal serotypes (PCV7) reduced disease prevalence due to antibiotic-resistant strains throughout the 2000s. However, diseases caused by resistant nonvaccine type (NVT) strains increased. Some of these emerging strains were derived from vaccine types (VT) that had changed their capsule by recombination. The introduction of a vaccine targeting 13 serotypes (PCV13) in 2010...

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Identifiers

PMID: 28100596
DOI: 10.1128/JCM.02453-16
PMCID: PMC5377837

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Source receipt: pubmed, retrieved 7 Sept 2026.

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