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Article

Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation

1 Feb 2019

Abstract excerpt

Aquaporin-1 (AQP1) is a homo-tetrameric transmembrane protein that facilitates rapid movement of water and ions across cell membranes. The clinical significance of AQP1 expression in colorectal carcinoma (CRC) is controversial. The aim of this study was to investigate the prognostic significance of AQP1 transcript expression and the association between expression and promoter methylation in normal colonic mucosa,...

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PMID: 30739527
DOI: 10.1080/15592294.2019.1580112

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