Article
Aquaporin 1 protein expression is associated with BRAF V600 mutation and adverse prognosis in cutaneous melanoma.
Melanoma research - 1 Jun 2016
Imrédi Eleonóra, Tóth Béla, Doma Viktória, Barbai Tamás, Rásó Erzsébet, Kenessey István, Tímár József
Abstract excerpt
Despite experimental findings suggesting the prognostic significance of Aquaporin 1 (AQP1) in human melanoma, no published clinical data are available. We studied the expression of AQP1 protein in cutaneous melanoma, correlated our findings with standard histological and genetic markers, and long-term clinical follow-up. Our study evaluated the AQP1 protein expression in 78 melanoma patients, representing two...
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