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From Mother to Child: Epigenetic Signatures of Hyperglycemia and Obesity during Pregnancy

16 Oct 2024

Abstract excerpt

Background: In utero exposure to maternal hyperglycemia and obesity can trigger detrimental effects in the newborn through epigenetic programming. We aimed to assess the DNA methylation levels in the promoters of MC4R and LPL genes from maternal blood, placenta, and buccal swab samples collected in children born to mothers with and without obesity and Gestational Diabetes Mellitus (GDM). Methods: A total of 101...

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PMID: 39458497
DOI: 10.3390/nu16203502

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