Article

Maternal underweight and obesity are associated with placental pathologies in human pregnancy

2021-06-04

Abstract excerpt

<h4>Introduction</h4> Maternal underweight and obesity are prevalent conditions, associated with chronic, low-grade inflammation, poor fetal development, and long-term adverse outcomes for the child. The placenta senses and adapts to the pregnancy environment in an effort to support optimal fetal development. However, the mechanisms driving these adaptations, and the resulting placental phenotypes, are poorly unde...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eabba45f-e5cb-5319-9ba3-4cd29385001b
DOI: 10.1101/2021.06.01.21258127

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Maternal underweight and obesity are associated with placental pathologies in human pregnancyDOI 10.1101/2021.06.01.21258127Read

Gestational age and infection are greater predictors of placental histopathology than maternal prepregnancy BMISemantic proximity Read

Sex Specificities of Human Placental Adaptive Changes: The Influence of Maternal ObesitySemantic proximity Read

Placental inflammation, oxidative stress, and fetal outcomes in maternal obesitySemantic proximity Read

Altered Placental Morphology and Metabolomic Profile in Association with Uncomplicated Metabolically Healthy Obese PregnancySemantic proximity Read

Pre-pregnancy BMI-associated miRNA and mRNA expression signatures in the placenta highlight a sexually-dimorphic response to maternal underweight statusSemantic proximity Read

Altered placental morphology and metabolomic profile in association with uncomplicated metabolically healthy obese pregnancySemantic proximity Read

Maternal BMI and Placental Transcriptomic Changes: A Meta-Analysis of Gene Expression at the Maternal-Fetal InterfaceSemantic proximity Read

Placental adaptation to maternal malnutritionSemantic proximity Read

Placental Dysfunction and Fetal Programming: The Importance of Placental Size, Shape, Histopathology, and Molecular CompositionSemantic proximity Read

Impact of maternal obesity on placental transcriptome and morphology associated with fetal growth restriction in miceSemantic proximity Read

Abnormal Placentation Associated with Infertility as a Marker of Overall HealthSemantic proximity Read

Association between placental efficiency with anthropometry and nutritional phenotypes in full-term newborns from the 2010/2011 BRISA birth cohort.Semantic proximity Read