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Article

Diagnosing hereditary cancer predisposition in men with prostate cancer.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2020

Pritzlaff Mary, Tian Yuan, Reineke Patrick, Stuenkel A J, Allen Kyle, Gutierrez Stephanie, Jackson Michelle, Dolinsky Jill S, LaDuca Holly, Xu Jianfeng, Black Mary Helen, Helfand Brian T

Abstract excerpt

PURPOSE: We describe the pathogenic variant spectrum and identify predictors of positive results among men referred for clinical genetic testing for prostate cancer. METHODS: One thousand eight hundred twelve men with prostate cancer underwent clinical multigene panel testing between April 2012 and September 2017. Stepwise logistic regression determined the most reliable predictors of positive results among...

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32439974
DOI: 10.1038/s41436-020-0830-5
PMCID: PMC7462744

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