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Article

Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes

30 Jan 2019

Abstract excerpt

MOTIVATION: Medulloblastoma (MB) is a brain cancer predominantly arising in children. Roughly 70% of patients are cured today, but survivors often suffer from severe sequelae. MB has been extensively studied by molecular profiling, but often in small and scattered cohorts. To improve cure rates and reduce treatment side effects, accurate integration of such data to increase analytical power will be important, if...

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PMID: 30715209
DOI: 10.1093/bioinformatics/btz066

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