Article
The function of TRPS1 in the development and differentiation of bone, kidney, and hair follicles.
Histology and histopathology - 1 Jul 2011
Gai Zhibo, Gui Ting, Muragaki Yasuteru
Abstract excerpt
TRPS1 is a gene involved in Tricho-rhino-phalangeal syndrome (TRPS), an autosomal dominant skeletal disorder. TRPS1 encodes a GATA-type transcription factor that has nine zinc-finger motifs. A variety of mutations in TRPS1 including deletions and insertions, have been found in patients with TRPS type I and III. The functions of each domain of TRPS1 have been clarified from study of these mutations. Further...
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