Article
Maternal Lactase Polymorphism (rs4988235) Is Associated with Neural Tube Defects in Offspring in the National Birth Defects Prevention Study.
The Journal of nutrition - 1 Feb 2019
Hoang Thanh T, Lei Yunping, Mitchell Laura E, Sharma Shreela V, Swartz Michael D, Waller D Kim, Finnell Richard H, Benjamin Renata H, Browne Marilyn L, Canfield Mark A, Lupo Philip J, McKenzie Paige, Shaw Gary, Agopian A J
Abstract excerpt
BACKGROUND: The risk of neural tube defect (NTD)-affected pregnancies is reduced with adequate folic acid intake during early pregnancy. However, NTDs have been observed among offspring of women with adequate folic acid intake. Some of these women are possibly not absorbing enough folic acid. Because lactase deficiency can lead to poor nutrient absorption, we hypothesized that lactase-deficient women will be at...
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