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Article

Loss of atypical chemokine receptor 4 facilitates C‑C motif chemokine ligand 21‑mediated tumor growth and invasion in nasopharyngeal carcinoma

23 Nov 2018

Abstract excerpt

Nasopharyngeal carcinoma (NPC) is a common malignant disease that is prevalent in Asian countries. Atypical chemokine receptor 4 (ACKR4) binds to various chemokines, including C‑C motif chemokine ligand (CCL)19, CCL21, CCL25 and C‑X‑C motif chemokine ligand 13, without inducing downstream signaling transduction. However, the role of ACKR4 in modulating NPC development remains unclear. In the present study, the...

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PMID: 30651842
DOI: 10.3892/etm.2018.7007

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