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Article

Prenatal Fish Oil Supplementation, Maternal COX1 Genotype, and Childhood Atopic Dermatitis: A Secondary Analysis of a Randomized Clinical Trial.

JAMA dermatology - 1 Oct 2024

Chen Liang, Brustad Nicklas, Luo Yang, Wang Tingting, Ali Mina, Ebrahimi Parvaneh, Schoos Ann-Marie M, Vahman Nilo, Lovric Mario, Rasmussen Morten A, Kolmert Johan, Wheelock Craig E, Lasky-Su Jessica A, Stokholm Jakob, Bønnelykke Klaus, Chawes Bo

Abstract excerpt

Importance: Eicosanoids have a pathophysiological role in atopic dermatitis (AD), but it is unknown whether this is affected by prenatal ω-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA; ie, fish oil) supplementation and genetic variations in the cyclooxygenase-1 (COX1) pathway. Objective: To explore the association of n-3 LCPUFA supplementation during pregnancy with risk of childhood AD overall and by...

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Identifiers

PMID: 39196551
DOI: 10.1001/jamadermatol.2024.2849
PMCID: PMC11359109

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