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Concise Review: Human-Animal Neurological Chimeras: Humanized Animals or Human Cells in an Animal?

10 Jan 2019

Abstract excerpt

Blastocyst complementation is an emerging methodology in which human stem cells are transferred into genetically engineered preimplantation animal embryos eventually giving rise to fully developed human tissues and organs within the animal host for use in regenerative medicine. The ethical issues surrounding this method have caused the National Institutes of Health to issue a moratorium on funding for blastocyst...

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PMID: 30629789
DOI: 10.1002/stem.2971

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