Article
Behavioral and histopathological assessment of adult ischemic rat brains after intracerebral transplantation of NSI-566RSC cell lines.
PloS one - 1 Jan 2014
Tajiri Naoki, Quach David M, Kaneko Yuji, Wu Stephanie, Lee David, Lam Tina, Hayama Ken L, Hazel Thomas G, Johe Karl, Wu Michael C, Borlongan Cesar V
Abstract excerpt
Stroke is a major cause of death and disability, with very limited treatment option. Cell-based therapies have emerged as potential treatments for stroke. Indeed, studies have shown that transplantation of neural stem cells (NSCs) exerts functional benefits in stroke models. However, graft survival and integration with the host remain pressing concerns with cell-based treatments. The current study set out to...
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