Article

What is a Humanized Mouse? Remaking the Species and Spaces of Translational Medicine

2012-08-30

Abstract excerpt

This article explores the development of a novel biomedical research organism, and its potential to remake the species and spaces of translational medicine. The humanized mouse is a complex experimental object in which mice, rendered immunodeficient through genetic alteration, are engrafted with human stem cells in the hope of reconstituting a human immune system for biomedical research and drug testing. These chi...

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Identifiers and source

Literature Corpus work: deeb5c73-42fe-5ecb-8735-bf54d700c9a4
DOI: 10.1177/1357034x12446378

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