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Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer

10 Jan 2019

Abstract excerpt

Polycomb group proteins are important epigenetic regulators for cell proliferation and differentiation, organ development, as well as initiation and progression of lethal diseases, including cancer. Upregulated Polycomb group proteins, including Enhancer of zeste homolog 2 (EZH2), promote proliferation, migration, invasion and metastasis of cancer cells, as well as self-renewal of cancer stem cells. In our study,...

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Share to Epigenetics and DNA Methylation
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PMID: 30628724
DOI: 10.1002/ijc.32118

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