Article
Receptor activity-modifying protein 1 regulates the phenotypic expression of BMSCs via the Hippo/Yap pathway.
Journal of cellular physiology - 1 Aug 2019
Zhang Qin, Guo Yanjun, Yu Hui, Tang Yufei, Yuan Ying, Jiang Yixuan, Chen Huilu, Gong Ping, Xiang Lin
Abstract excerpt
Receptor activity-modifying protein 1 (RAMP1) might be a critical regulator during bone wound healing. However, the roles and mechanisms of RAMP1 in osteogenesis remain unclear. Here, we aimed to elucidate the role of RAMP1 and explore the effects of Yes-associated protein 1 (Yap1), an effector of the Hippo/Yap pathway, in this process. We used a RAMP1 overexpression lentiviral system in bone marrow mesenchymal...
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