Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

STAT3 Regulates the Onset of Oxidant-induced Senescence in Lung Fibroblasts

4 Jan 2019

Abstract excerpt

Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease of unknown cause with a median survival of only 3 years. Other investigators and we have shown that fibroblasts derived from IPF lungs display characteristics of senescent cells, and that dysregulated activation of the transcription factor signal transducer and activator of transcription 3 (STAT3) correlates with IPF progression. The question...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to NF-κB Signaling Pathways
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30608861
DOI: 10.1165/rcmb.2018-0328oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

STAT3 Regulates the Onset of Oxidant-induced Senescence in Lung FibroblastsPMID 30608861Read ↗

Fibroblast senescence in the pathology of idiopathic pulmonary fibrosisSemantic proximity Read ↗

Fibroblast Senescence in Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Cellular Senescence in Aging Lungs and DiseasesSemantic proximity Read ↗

Stimuli-Specific Senescence of Primary Human Lung Fibroblasts Modulates Alveolar Stem Cell FunctionSemantic proximity Read ↗

Mitochondrial dysfunction and alveolar type II epithelial cell senescence: The destroyer and rescuer of idiopathic pulmonary fibrosisSemantic proximity Read ↗

IPF lung fibroblasts have a senescent phenotypeSemantic proximity Read ↗

Molecular Mechanisms of Alveolar Epithelial Stem Cell Senescence and Senescence-Associated Differentiation Disorders in Pulmonary FibrosisSemantic proximity Read ↗

Cellular senescence in asthma: from pathogenesis to therapeutic challenges.Semantic proximity Read ↗

Cellular Senescence in Lung FibrosisSemantic proximity Read ↗

Cellular Senescence: A Troy Horse in Pulmonary FibrosisSemantic proximity Read ↗

Hypoxia-inducible factor and cellular senescence in pulmonary aging and diseaseSemantic proximity Read ↗

Lung Fibroblasts, Aging, and Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.