Article
The use of targeted sequencing and flow cytometry to identify patients with a clinically significant monocytosis
3 Jan 2019
Abstract excerpt
Abstract The diagnosis of chronic myelomonocytic leukemia (CMML) remains centered on morphology, meaning that the distinction from a reactive monocytosis is challenging. Mutational analysis and immunophenotyping have been proposed as potential tools for diagnosis; however, they have not been formally assessed in combination. We aimed to investigate the clinical utility of these technologies by performing targeted...
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