miR-222-3p promotes osteosarcoma cell migration and invasion through targeting TIMP3

Abstract excerpt

BACKGROUND: Abnormal expression of miRNAs has been reported in osteosarcoma (OS), and miR-222-3p levels have been found to be increased in the serum of OS patients. However, the exact role of miR-222-3p in OS remains unclear. In the present study, we aimed to identify the molecular mechanism underlying the role of miR-222-3p in the development of OS. METHODS: We examined the expression level of miR-222-3p in OS...

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