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Article

MicroRNA-532-5p is a prognostic marker and inhibits the aggressive phenotypes of osteosarcoma through targeting CXCL2.

The Kaohsiung journal of medical sciences - 1 Nov 2020

Ma Yong, Zhao Hai-Xia, Shi Yin-Ju, Cheng Ming-Guo

Abstract excerpt

The dysregulation of miR-532-5p is involved in the development of several cancers. Nevertheless, the roles of miR-532-5p in osteosarcoma (OS) have yet to be illuminated. In the present study, we found that miR-532-5p was significantly downregulated in both OS tissues and cell lines. The low level of miR-532-5p was associated with advance clinical stage and poor overall survival in patient with OS. The functional...

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PMID: 32643867
DOI: 10.1002/kjm2.12261

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