Article
Clinical and Functional Significance of Intracellular and Extracellular microRNA-25-3p in Osteosarcoma.
Acta medica Okayama - 1 Apr 2018
Yoshida Aki, Fujiwara Tomohiro, Uotani Koji, Morita Takuya, Kiyono Masahiro, Yokoo Suguru, Hasei Joe, Nakata Eiji, Kunisada Toshiyuki, Ozaki Toshifumi
Abstract excerpt
Although there is considerable evidence indicating that the dysregulation of microRNAs (miRNAs) in malignant tumors plays a role in tumor development, the overall function of miRNAs and their clinicopathological significance are not well understood. In this retrospective analysis of 45 biopsy specimens from osteosarcoma (OS) patients, we investigated the functional and clinical significance of miR-25-3p in OS,...
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