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Article

Analysis of PD-1 related immune transcriptional profile in different cancer types

1 Dec 2018

Abstract excerpt

BACKGROUND: Programmed cell death 1 (PD-1) functions as an immune checkpoint in the process of anti-tumor immune response. The PD-1 blockade is now becoming a fundamental part in cancer immunotherapy. So it's essential to elicit the PD-1 related immune process in different types of cancer. METHODS: The Cancer Genome Atlas was used to collect the RNA-seq data of 33 cancer types. The microenvironment cell...

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PMID: 30607140
DOI: 10.1186/s12935-018-0712-y

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