Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic and Genetic Regulation of PDCD1 Gene in Cancer Immunology.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Mishra Alok, Verma Mukesh

Abstract excerpt

Utilizing biology of PD-1: PD-L1 interaction related pathways for cancer immunotherapy is an emerging concept in cancer research. However, there is limited literature on epigenetic regulation of PD1 gene (PDCD1). Promising data from clinical trials of PD/PDl-1 immunotherapy in melanoma, renal cancers, colorectal and lung cancers has generated a lot of hope for successful treatment of patients. Immunotherapy in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Epigenesis, Genetic
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to Immunomodulation

Share to Neoplasms

Share to Programmed Cell Death 1 Receptor

Source

Identifiers

PMID: 30178256
DOI: 10.1007/978-1-4939-8751-1_14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic and Genetic Regulation of PDCD1 Gene in Cancer Immunology.PMID 30178256Read ↗

Epigenetic modifications: Critical participants of the PD‑L1 regulatory mechanism in solid tumors (Review)Semantic proximity Read ↗

Gene code CD274/PD-L1 : from molecular basis toward cancer immunotherapySemantic proximity Read ↗

Complex regulatory network of programmed death-ligand 1 in cancer: Cancer immunomodulation from molecular mechanisms to clinical applicationsSemantic proximity Read ↗

PD-L1: expression regulationSemantic proximity Read ↗

Targeting the PD-1/PD-L1 Signaling Pathway for Cancer Therapy: Focus on BiomarkersSemantic proximity Read ↗

Targeting the PD-1/PD-L1 Signaling Pathway for Cancer Therapy: Focus on BiomarkersSemantic proximity Read ↗

Recent Findings in the Regulation of Programmed Death Ligand 1 ExpressionSemantic proximity Read ↗

New insights into epigenetic regulation of resistance to PD-1/PD-L1 blockade cancer immunotherapy: mechanisms and therapeutic opportunitiesSemantic proximity Read ↗

Genetic and Epigenetic Regulation of PD-1 ExpressionSemantic proximity Read ↗

Analysis of PD-1 related immune transcriptional profile in different cancer typesSemantic proximity Read ↗

Research progress on the intrinsic non‑immune function of PD‑L1 in tumors (Review)Semantic proximity Read ↗

Epigenome-Driven Strategies for Personalized Cancer ImmunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.