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Long Non-Coding RNAs Associated with Heterochromatin Function in Immune Cells in Psychosis

18 Dec 2018

Abstract excerpt

Psychosis is associated with chronic immune dysregulation. Many long non-coding RNAs (lncRNAs) display abnormal expression during activation of immune responses, and play a role in heterochromatic regulation of gene promoters. We have measured lncRNAs MEG3, PINT and GAS5, selected for their previously described association with heterochromatin. Peripheral blood mononuclear cells (PBMCs) were isolated from blood...

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PMID: 30567388
DOI: 10.3390/ncrna4040043

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