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Article

Sox2 is associated with cancer stem-like properties in colorectal cancer

29 Nov 2018

Abstract excerpt

Abstract Sox2 is known as the undifferentiated cell marker. Recent studies have shown that Sox2 may also be involved in the maintenance of cancer stem cells (CSCs) in skin and bladder cancers. In this study, we aimed to clarify the role of Sox2 in colorectal CSCs. Sox2 expression was measured in colon cancer cells and colorectal clinical samples by qRT-PCR and western blot analysis. To visualize the active Sox2...

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PMID: 30518951
DOI: 10.1038/s41598-018-36251-0

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