Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for Less Marked Potential Signs of T-Cell Immunosenescence in Centenarian Offspring Than in the General Age-Matched Population

24 Aug 2013

Abstract excerpt

People may reach the upper limits of the human life span at least partly because they have maintained more appropriate immune function, avoiding changes to immunity termed "immunosenescence." Exceptionally long-lived people may be enriched for genes that contribute to their longevity, some of which may bear on immune function. Centenarian offspring would be expected to inherit some of these, which might be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23974207
DOI: 10.1093/gerona/glt120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for Less Marked Potential Signs of T-Cell Immunosenescence in Centenarian Offspring Than in the General Age-Matched PopulationPMID 23974207Read ↗

Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenariansSemantic proximity Read ↗

Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevitySemantic proximity Read ↗

Hallmark Features of Immunosenescence Are Absent in Familial LongevitySemantic proximity Read ↗

Inflammation and Genetics: An Insight in the Centenarian ModelSemantic proximity Read ↗

Sexual dimorphism in immunity and longevity among the oldest oldSemantic proximity Read ↗

Genetic Signatures of Centenarians: Implications for Achieving Successful Aging.Semantic proximity Read ↗

Human ImmunosenescenceSemantic proximity Read ↗

Leukocyte telomere length and prevalence of age-related diseases in semisupercentenarians, centenarians and centenarians' offspringSemantic proximity Read ↗

Gender, aging and longevity in humans: an update of an intriguing/neglected scenario paving the way to a gender-specific medicineSemantic proximity Read ↗

Does the human immune system ever really become “senescent”?Semantic proximity Read ↗

A review of centenarian studiesSemantic proximity Read ↗

Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenariansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.