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Article

miR-200b suppresses invasiveness and modulates the cytoskeletal and adhesive machinery in esophageal squamous cell carcinoma cells via targeting Kindlin-2.

Carcinogenesis - 1 Feb 2014

Zhang Hai-Feng, Zhang Kai, Liao Lian-Di, Li Li-Yan, Du Ze-Peng, Wu Bing-Li, Wu Jian-Yi, Xu Xiu-E, Zeng Fa-Min, Chen Bo, Cao Hui-Hui, Zhu Meng-Xiao, Dai Li-Hua, Long Lin, Wu Zhi-Yong, Lai Raymond, Xu Li-Yan, Li En-Min

Abstract excerpt

To further our understanding of the pathobiology of esophageal squamous cell carcinoma (ESCC), we previously performed microRNA profiling that revealed downregulation of miR-200b in ESCC. Using quantitative real-time PCR applied to 88 patient samples, we confirmed that ESCC tumors expressed significantly lower levels of miR-200b compared with the respective adjacent benign tissues (P = 0.003). Importantly,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24064224
DOI: 10.1093/carcin/bgt320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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