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Article

Inhibition of long non-coding RNA HOTAIR enhances radiosensitivity via regulating autophagy in pancreatic cancer

1 Nov 2018

Abstract excerpt

BACKGROUND: Resistance to radiation therapy is still a challenge for treatment of pancreatic cancer(PC). Long non-coding RNAs (lncRNA) HOTAIR has been found to play a oncogenic role in several cancers. However, the correlation between HOTAIR and radiotherapy in PC is still unclear. METHODS: TCGA data was collected to analyze the expression of HOTAIR and its relationship with PC progression. A series of functional...

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PMID: 30464623
DOI: 10.2147/cmar.s174066

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