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Article

LncRNA HOTAIR promotes DNA damage repair and radioresistance by targeting ATR in colorectal cancer

1 Jan 2024

Abstract excerpt

Long non-coding RNAs (lncRNAs) have been implicated in cancer progression and drug resistance development. Moreover, there is evidence that lncRNA HOX transcript antisense intergenic RNA (HOTAIR) is involved in colorectal cancer (CRC) progression. The present study aimed to examine the functional role of lncRNA HOTAIR in conferring radiotherapy resistance in CRC cells, as well as the underlying mechanism. The...

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PMID: 39055884
DOI: 10.32604/or.2024.044174

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