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Article

Expression of the POTE gene family in human ovarian cancer

14 Nov 2018

Abstract excerpt

The POTE family includes 14 genes in three phylogenetic groups. We determined POTE mRNA expression in normal tissues, epithelial ovarian and high-grade serous ovarian cancer (EOC, HGSC), and pan-cancer, and determined the relationship of POTE expression to ovarian cancer clinicopathology. Groups 1 & 2 POTEs showed testis-specific expression in normal tissues, consistent with assignment as cancer-testis antigens...

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PMID: 30459449
DOI: 10.1038/s41598-018-35567-1

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