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Article

Single-cell RNA-seq highlights a specific carcinoembryonic cluster in ovarian cancer

13 Nov 2021

Abstract excerpt

Abstract Expounding the heterogeneity for ovarian cancer (OC) with the cognition in developmental biology might be helpful to search for robust prognostic markers and effective treatments. In the present study, we employed single-cell RNA-seq with ovarian cancers, normal ovary, and embryo tissue to explore their heterogeneity. Then the differentiation process of clusters was explored; the pivotal cluster and...

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PMID: 34775482
DOI: 10.1038/s41419-021-04358-4

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