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Article

TLR9 Contributes to Antiviral Immunity during Gammaherpesvirus Infection

1 Jan 2008

Abstract excerpt

The human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and EBV cause important infections. As pathogenetic studies of the human infections are restricted, murine gammaherpesvirus 68 serves as a model to study gammaherpesvirus pathogenesis. TLRs are a conserved family of receptors detecting microbial molecular patterns. Among the TLRs, TLR9 recognizes unmethylated CpG DNA motifs present in bacterial...

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PMID: 18097045
DOI: 10.4049/jimmunol.180.1.438

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