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Article

Identification of TEX101-associated Proteins Through Proteomic Measurement of Human Spermatozoa Homozygous for the Missense Variant rs35033974*

15 Nov 2018

Abstract excerpt

TEX101 is a germ-cell-specific protein and a validated biomarker of male infertility. Mouse TEX101 was found essential for male fertility and was suggested to function as a cell surface chaperone involved in maturation of proteins required for sperm migration and sperm–oocyte interaction. However, the precise functional role of human TEX101 is not known and cannot be studied in vitro due to the lack of human germ...

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PMID: 30429210
DOI: 10.1074/mcp.ra118.001170

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Identification of TEX101-associated Proteins Through Proteomic Measurement of Human Spermatozoa Homozygous for the Missense Variant rs35033974*PMID 30429210Read ↗

Identification of TEX101 functional interactome through proteomic measurement of human spermatozoa homozygous for the missense variant rs35033974Semantic proximity Read ↗

TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.Semantic proximity Read ↗

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Differential Diagnosis of Azoospermia with Proteomic Biomarkers ECM1 and TEX101 Quantified in Seminal PlasmaSemantic proximity Read ↗

Scrutinizing the human TEX genes in the context of human male infertilitySemantic proximity Read ↗

<i>Tex11</i> Mutant Mouse Models of Human AzoospermiaSemantic proximity Read ↗

Genetic characterization of a missense mutation in the X-linked TAF7L gene identified in an oligozoospermic man†.Semantic proximity Read ↗

Identification of novel variants and expansion of the phenotypic spectrum in PATL2, WEE2, and TUBB8 associated with human early embryonic arrest.Semantic proximity Read ↗

Two Novel TEX15 Mutations in a Family with Nonobstructive Azoospermia.Semantic proximity Read ↗

Genomic organization and structure of the 5'-flanking region of the TEX101 gene: alternative promoter usage and splicing generate transcript variants with distinct 5'-untranslated region.Semantic proximity Read ↗

TEX43, a Testis-Enriched Microtubule-Associated Gene, Exerts Minimal Impact on Spermatogenesis and Fertility in Mice and HumansSemantic proximity Read ↗

Disruption of TEX38 impairs sperm morphogenesis and the migration of sperm into the oviductSemantic proximity Read ↗

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