Article
Exome Sequencing Identifies Susceptibility Loci for Sarcoidosis Prognosis.
Frontiers in immunology - 1 Jan 2019
Lahtela Elisa, Kankainen Matti, Sinisalo Juha, Selroos Olof, Lokki Marja-Liisa
Abstract excerpt
Many sarcoidosis-associating immunological genes have been shown to be shared between other immune-mediated diseases. In Finnish sarcoidosis patients, good prognosis subjects more commonly have HLA-DRB1*03:01 and/or HLA-DRB1*04:01-DPB1*04:01 haplotype, but no marker for persistent disease have been found. The objective was to further pinpoint genetic differences between prognosis subgroups in relation to the HLA...
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