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Article

βcatenin is a marker of poor clinical characteristics and suppressed immune infiltration in testicular germ cell tumors

3 Nov 2018

Abstract excerpt

BACKGROUND: WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. METHODS: Surgical specimens from 247 patients were analyzed. Βcatenin expression was detected in the tumor tissue by immunohistochemistry and correlated with clinical characteristics,...

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PMID: 30390643
DOI: 10.1186/s12885-018-4929-x

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