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Niche adaptation and viral transmission of human papillomaviruses from archaic hominins to modern humans

1 Nov 2018

Abstract excerpt

Recent discoveries on the origins of modern humans from multiple archaic hominin populations and the diversity of human papillomaviruses (HPVs) suggest a complex scenario of virus-host evolution. To evaluate the origin of HPV pathogenesis, we estimated the phylogeny, timing, and dispersal of HPV16 variants using a Bayesian Markov Chain Monte Carlo framework. To increase precision, we identified and characterized...

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PMID: 30383862
DOI: 10.1371/journal.ppat.1007352

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