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Gene therapy and type 1 diabetes mellitus

1 Oct 2018

Abstract excerpt

BACKGROUND: Type 1 diabetes mellitus (T1DM) is an autoimmune disorder characterized by T cell-mediated self-destruction of insulin-secreting islet β cells. Management of T1DM is challenging and complicated especially with conventional medications. Gene therapy has emerged as one of the potential therapeutic alternatives to treat T1DM. This review primarily focuses on the current status and the future perspectives...

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PMID: 30372820
DOI: 10.1016/j.biopha.2018.09.138

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