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Gene Therapy: Some History, Applications, Problems, and Prospects

1 Jan 2008

Abstract excerpt

The concept of transferring genes to tissues for clinical applications has been discussed for nearly half a century, but our ability to manipulate genetic material via recombinant DNA technology has brought this goal to reality. While originally conceived as a way to treat life-threatening disorders (inborn errors, cancers) refractory to conventional treatment, gene therapy now is considered for many...

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PMID: 18337227
DOI: 10.1177/0192623307309925

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