Gene therapy for diabetes mellitus.

doi:10.2174/1566524013363717

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Article

Gene therapy for diabetes mellitus.

Current molecular medicine - 1 Jul 2001

Yamaoka T

Abstract excerpt

There are diverse strategies for gene therapy of diabetes mellitus. Prevention of beta-cell autoimmunity is a specific gene therapy for prevention of type 1 (insulin-dependent) diabetes in a preclinical stage, whereas improvement in insulin sensitivity of peripheral tissues is a specific gene therapy for type 2 (non-insulin-dependent) diabetes. Suppression of beta-cell apoptosis, recovery from insulin deficiency,...

Topics

Amino Acid Sequence
Apoptosis
Autoimmunity
Cell Differentiation
Cell Division
Diabetes Mellitus
Genetic Engineering
Genetic Therapy
Humans
Insulin
Insulin Resistance
Insulin Secretion
Islets of Langerhans
Islets of Langerhans Transplantation
Molecular Sequence Data
Mutation
Proinsulin
Regeneration

Source

Open in PubMed

Identifiers

PMID: 11899081
DOI: 10.2174/1566524013363717

Provenance

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