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High‐throughput screening of antibody‐expressing CHO clones using an automated shaken deep‐well system

9 Oct 2018

Abstract excerpt

Biopharmaceutical protein manufacturing requires the highest producing cell lines to satisfy current multiple grams per liter requirements. Screening more clones increases the probability of identifying the high producers within the pool of available transfectant candidate cell lines. For the predominant industry mammalian host cell line, Chinese hamster ovary (CHO), traditional static-batch culture screening...

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PMID: 30298994
DOI: 10.1002/btpr.2721

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