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Article

Rearrangement and enhanced expression of c-myc in hepatocellular carcinoma of hepatitis virus infected woodchucks.

Nature - 1 Jan 2000

Möröy T, Marchio A, Etiemble J, Trépo C, Tiollais P, Buendia M A

Abstract excerpt

Hepatocellularcarcinoma (HCC) that occur in woodchucks chronically infected with woodchuck hepatitis virus (WHV) were screened for activation of cellular oncogenes. Enhanced expression and allelic alterations of the c-myc oncogene were found in three HCC out of nine. Variations in the size of the...

Topics

Alleles
Animals
Base Sequence
DNA Restriction Enzymes
Genes, Viral
Hepatitis Viruses
Liver Neoplasms, Experimental
Marmota
Nucleic Acid Hybridization
Oncogenes
RNA, Messenger
Transcription, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 3024010
DOI: 10.1038/324276a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-3024010-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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