Article
An autoantibody identifies arrhythmogenic right ventricular cardiomyopathy and participates in its pathogenesis
22 Aug 2018
Abstract excerpt
Aims: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by right ventricular myocardial replacement and life-threatening ventricular arrhythmias. Desmosomal gene mutations are sometimes identified, but clinical and genetic diagnosis remains challenging. Desmosomal skin disorders can be caused by desmosomal gene mutations or autoantibodies. We sought to determine if anti-desmosome antibodies...
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