Non-cyp51AAzole-ResistantAspergillus fumigatusIsolates with Mutation in HMG-CoA Reductase

Abstract excerpt

The recent increase in azole-resistant Aspergillus fumigatus is a global concern. Identifying the mutations that confer azole resistance is essential for developing novel methods for prompt diagnosis and effective drug treatment. We screened A. fumigatus clinical isolates for novel mutations conferring azole resistance. We compared the genomic sequences of susceptible and resistant isolates without mutations in...

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