Article
Novel digital signatures of tissue phenotypes for predicting distant metastasis in colorectal cancer.
Scientific reports - 12 Sept 2018
Sirinukunwattana Korsuk, Snead David, Epstein David, Aftab Zia, Mujeeb Imaad, Tsang Yee Wah, Cree Ian, Rajpoot Nasir
Abstract excerpt
Distant metastasis is the major cause of death in colorectal cancer (CRC). Patients at high risk of developing distant metastasis could benefit from appropriate adjuvant and follow-up treatments if stratified accurately at an early stage of the disease. Studies have increasingly recognized the role of diverse cellular components within the tumor microenvironment in the development and progression of CRC tumors....
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