Article
Pathogenesis of asthma: implications for precision medicine.
Clinical science (London, England : 1979) - 15 Jul 2017
Russell Richard J, Brightling Christopher
Abstract excerpt
The pathogenesis of asthma is complex and multi-faceted. Asthma patients have a diverse range of underlying dominant disease processes and pathways despite apparent similarities in clinical expression. Here, we present the current understanding of asthma pathogenesis. We discuss airway inflammation (both T2HIGH and T2LOW), airway hyperresponsiveness (AHR) and airways remodelling as four key factors in asthma...
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