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Article

Visualisation and analysis of hepatitis C virus non-structural proteins using super-resolution microscopy.

Scientific reports - 11 Sept 2018

Bartlett Christopher, Curd Alistair, Peckham Michelle, Harris Mark

Abstract excerpt

Hepatitis C virus (HCV) RNA replication occurs in the cytosol of infected cells within a specialised membranous compartment. How the viral non-structural (NS) proteins are associated and organised within these structures remains poorly defined. We employed a super-resolution microscopy approach to visualise NS3 and NS5A in HCV infected cells. Using single molecule localisation microscopy, both NS proteins were...

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Identifiers

PMID: 30206266
DOI: 10.1038/s41598-018-31861-0
PMCID: PMC6134135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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