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Article

Polymorphisms of Genes Related to Function and Metabolism of Vitamin D in Esophageal Adenocarcinoma.

Journal of gastrointestinal cancer - 1 Dec 2019

Singhal Saurabh, Kapoor Harit, Subramanian Saravanan, Agrawal Devendra K, Mittal Sumeet K

Abstract excerpt

PURPOSE: The vitamin D receptor (VDR) endocrine system has emerged as an endogenous pleiotropic biological cell regulator with anti-neoplastic effects on breast, colorectal, and prostatic adenocarcinomas. We studied the association of gene expression, polymorphisms of VDR, CYP27B1, and CYP24A1 genes and serum vitamin D levels as surrogate markers of disease progression in patients with acid reflux, Barrett's...

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PMID: 30187205
DOI: 10.1007/s12029-018-0164-6

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