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Association of Vitamin D Receptor and Vitamin D-Binding Protein Polymorphisms with Familial Breast Cancer Prognosis in a Mono-Institutional Cohort.

Nutrients - 6 Apr 2021

Aristarco Valentina, Johansson Harriet, Gandini Sara, Macis Debora, Zanzottera Cristina, Tolva Gianluca, Feroce Irene, Accornero Chiara, Bonanni Bernardo, Guerrieri-Gonzaga Aliana, Serrano Davide

Abstract excerpt

Low 25-hydroxyvitamin D (25OHD) has been associated with an increased cancer incidence and poorer prognosis. Single nucleotide polymorphisms (SNPs) of vitamin D receptor (VDR) and vitamin D binding protein (GC gene) may interfere with vitamin D activity. This study assesses the role of VDR and GC SNPs on breast cancer (BC) recurrence and survival in a cohort of patients with a family history of breast cancer,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

Share to Polymorphism, Restriction Fragment Length

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Identifiers

PMID: 33917614
DOI: 10.3390/nu13041208
PMCID: PMC8067530

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